lipid metabolism — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN6772	Malabaricone C		Others
	Malabaricone C is a bioactive chemical.		Others
T3804	Neomangiferin	Mangiferin 7-glucoside	Phosphatase
	Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a biochemical mar...		Phosphatase
T4039	BIBB 515		Others
	BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of...		Others
T3124	Carbendazim	Bavistin,Carbendazole,Mercarzole	Antifungal
	Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspec...		Antifungal
T35343	MTI-31	MTI-31,LXI-15029	mTOR
	MTI-31 (LXI-15029) is a potent, orally active and highly selective inhibitor of mTORC1 and mTORC2. MTI-31 is selective for mTOR (Kd: 0.20 nM) versus PIK3CA, PIK3CB and PIK3G with >5,000 fold selectivity in mTOR binding a...		mTOR
T0700	Ursodeoxycholic acid	UDCA,Ursodiol	Potassium Channel , Endogenous Metabolite
	Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.		Potassium Channel , Endogenous Metabolite
T29078	Ursodeoxycholic acid sodium	UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium	FXR , Endogenous Metabolite , GPCR19
	Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it...		FXR , Endogenous Metabolite , GPCR19
T37958	Acetyl Coenzyme A trisodium	Acetyl-CoA trisodium	OXPHOS , Endogenous Metabolite , Autophagy
	Acetyl Coenzyme A trisodium (Acetyl-CoA trisodium) is an important compound in glucose metabolism and lipid metabolism and is involved in the tricarboxylic acid cycle.		OXPHOS , Endogenous Metabolite , Autophagy
T22708	Darglitazone	CP-86325	PPAR
	Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid metabolism.		PPAR
T0800	Danthron	Dantron,1,8-Dihydroxyanthraquinone,Chrysazin,Antrapurol	Virus Protease , Antibacterial , AMPK , Autophagy
	Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.		Virus Protease , Antibacterial , AMPK , Autophagy
T8714	1-Stearoyl-sn-glycero-3-phosphocholine	1-stearoyl-lysophosphatidylcholine,L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY	Others
	1-Stearoyl-sn-glycero-3-phosphocholine (L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY) is a chemical used in lipid metabolism studies		Others
T4461	3,5-Diiodo-L-thyronine	Diiodothyronine	Thyroid hormone receptor(THR) , Endogenous Metabolite
	3,5-Diiodo-L-thyronine (Diiodothyronine) is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance.		Thyroid hormone receptor(THR) , Endogenous Metabolite
T2867	Diosgenin	Nitogenin	STAT
	Diosgenin (Nitogenin) is a spirostan found in DIOSCOREA and other plants. It has favorable effects in the improvement of diabetes and regulation of lipid metabolism.		STAT
T14149	AICAR phosphate	AICA Riboside phosphate,Acadesine phosphate	Mitophagy , NOS , YAP , AMPK
	AICAR phosphate (Acadesine phosphate) is an AMPK activator and inhibitor of autophagy, YAP, and mitophagy, as well as an adenosine analog that regulates glucose and lipid metabolism, and inhibits the production of pro-in...		Mitophagy , NOS , YAP , AMPK
T1869	PluriSIn 1	NSC 14613,PluriSIn #1,PluriSln 1	Apoptosis , Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	PluriSIn 1 (NSC 14613) is an inhibitor of stearoyl-CoA desaturase (SCD1), the key enzyme in oleic acid biosynthesis, revealing a unique role for lipid metabolism in hPSCs.		Apoptosis , Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
TMA2440	Uridine 5'-monophosphate disodium salt	Disodium UMP,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate	Others
	Uridine 5'-monophosphate disodium salt (Disodium UMP) has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism. It has been used to study the effect of nucle...		Others
TP2018L	GIP (human) acetate	GIP (human) acetate(100040-31-1 Free base)	IGF-1R
	GIP (human) acetate is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP (human) acetate plays a vital role in lipid metabolism and the development of obesity.		IGF-1R
T67766	HHS-0701		Others
	HHS-0701 is a sulfur-triazole exchange (SuTEx) ligand. HHS-0701 is a potent inhibitor of tyrosine-reactive prostaglandin reductase 2 (PTGR2). HHS-0701 can block PTGR2 metabolism of the lipid substrate 15-Keto-PGE2.		Others
T1039	Choline chloride	Biocolina,Biocoline,Hepacholine	AChR
	Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in li...		AChR
T5249	1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine	1,2-DSPE,1,2-Distearoyl-sn-glycero-3-phosphoethan	Others , Endogenous Metabolite
	1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (1,2-DSPE) is a phosphatidylethanolamine (PE or GPEtn). The stearic acid moieties are derived from animal fats, coco butter, and sesame oil. Phospholipids, are ubiquitou...		Others , Endogenous Metabolite